The buildup of uric acid in your joints can lead to swollen growths under your skin called tophi. If left untreated, tophi can lead to loss of motion in your joints and other complications. A tophus ...

Please provide your email address to receive an email when new articles are posted on . One of the thrilling aspects of scientific discovery is that it can come from almost anywhere, and almost anyone ...

Please provide your email address to receive an email when new articles are posted on . Un-calcified tophaceous deposits that were undetected with conventional radiography may be visible on ...

Background: The prevalence of gout is increasing, and most research on the associated burden has focused on serum urate (sUA) levels. The present study quantifies the impact of the presence of tophi ...

Gout is a painful form of arthritis that occurs when too much uric acid builds up in the body. Uric acid is a normal waste product in the blood that comes from the breakdown of certain foods. Having ...

Many people who experience one gout attack never have a second attack. Others develop chronic gout or repeated attacks that happen more often over time. Chronic gout can lead to more severe problems, ...

Credit: Shutterstock. The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum ...

Tophaceous gout is a severe form of gout that typically develops in people with chronic gout. Tophaceous gout happens when uric acid crystals form masses of white growths around the joints and tissues ...

GOUT - a condition which people commonly associate with a rich diet - is a disorder which causes painful attacks of arthritis in the joints of the foot, knee, ankle, hand and wrist and especially the ...

The characteristics of the sample are presented in Table 1 and Table 2. The average age was 60.9 years, and patients had been diagnosed an average of 12 years. Most were male (81%), and 38% were ...